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Childhood social class and cancer incidence: results of the globe study

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image for OpenScout resource :: Childhood social class and cancer incidence: results of the globe study

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Despite increased recognition of the importance of investigating socio-economic inequalities in health from a life course perspective, little is known about the influence of previous termchildhoodnext term socio-economic position (SEP) on previous termcancer incidence.next term The authors studied the association between father's occupation and adult previous termcancer incidencenext term by linking information from the longitudinal GLOBE study with the regional population-based Eindhoven previous termCancernext term Registry (the Netherlands) over a period of 14 years. In 1991, 18,973 participants (response rate 70.1%) of this study responded to a postal questionnaire, including questions on SEP in youth and adulthood. Respondents above the age of 24 were included (N = 12,978). Cox regression was used to calculate hazard ratios (HR) for all previous termcancersnext term as well as for the five most frequently occurring previous termcancersnext term by respondent's educational level or occupational previous termclass,next term and by father's occupational previous termclassnext term (adjusted for respondent's education and occupation). Respondents with a low educational level showed an increased risk of all previous termcancers,next term lung and breast previous termcancernext term (in women). Respondents with a low adult occupational level showed an increased risk of lung previous termcancernext term and a reduced risk of basal cell carcinoma. After adjustment for adult education and occupation, respondents whose father was in a lower occupational previous termclassnext term showed an increased risk of colorectal previous termcancernext term as compared to those with a father in the highest previous termsocial class.next term In contrast, respondents whose father was in a lower occupational previous termclass,next term showed a decreased risk of basal cell carcinoma as compared to those with a father in the highest occupational previous termclass.next term The association between previous termchildhoodnext term SEP and previous termcancer incidencenext term is less consistent than the association between adult SEP and previous termcancer incidence,next term but may exist for colorectal previous termcancernext term and basal cell carcinoma.

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en

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http://eprints.lse.ac.uk/36722/

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